Related Experiment Video
Updated: Jul 25, 2025

Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency
Published on: June 16, 2011
Determinants of Genomic Diversity and Impact of Mutations in SARS-CoV-2
Franklin Rómulo Aguilar-Gamboa1, Danny Omar Suclupe-Campos2
1Lambayeque Regional Hospital, Immunology and Virology Laboratories, Inmunología y Virología del Norte´s group, Lambayeque, Peru.
Abstract:
SARS-CoV-2 has spread widely throughout the world, and multiple mutations and variants of interest were detected in the late 2020 and continue to emerge. Although genetic diversity is common in RNA viruses, these variations at the genetic level have given it certain characteristics associated with transmission, resistance to neutralizing antibodies, and even suspected increased lethality. Better understanding of the genomic diversity in SARS-CoV-2 will help to take appropriate containment measures against the virus. It should be borne in mind that this diversity can originate anywhere in the world, especially in areas where there is a high number of infections. This highlights the need for continuous molecular surveillance to guide development, therapy, vaccine use and health policy.
More Related Videos
Related Concept Videos
Viral Mutations
Single Nucleotide Polymorphisms-SNPs
Mutations in Microorganisms
Mutation, Gene Flow, and Genetic Drift
Gene Evolution - Fast or Slow?
In contrast, regions which code...
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...

