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Updated: Jul 25, 2025

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Use of Dual Optical Tweezers and Microfluidics for Single-Molecule Studies
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Extending the Contacts Breaks the Flow
Amado Carreras-Sureda1, Christopher Henry1, Nicolas Demaurex1
1Department of Cell Physiology and Metabolism, University of Geneva, Geneva, Switzerland.
Contact (Thousand Oaks (Ventura County, Calif.))
|June 27, 2023
Abstract:
In this news and views, we discuss our recent publication where we described how ER-PM membrane contact sites (MCS) are modulated during store operated calcium entry (SOCE). We also examine why enforcing ER-PM MCS by tethering proteins does not not enhance, but rather inhibits SOCE.
Keywords:
electron microscopyendoplasmic reticulumplasma membranestore-operated calcium entry (SOCE) (SOC)tetherMore Related Videos
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