Psychometric properties and general population reference values for PROMIS Global Health in Hungary

Area of Science:

• Health Outcomes Research
• Psychometrics
• Public Health

Background:

• Patient-Reported Outcomes Measurement Information System-Global Health (PROMIS-GH) is a key generic health status measure.
• Validating PROMIS-GH in diverse linguistic and cultural contexts is crucial for its global utility.
• Establishing population-specific reference values enhances the interpretability of patient scores.

Purpose of the Study:

• To assess the psychometric properties of the Hungarian version of PROMIS-GH.
• To develop general population reference values for PROMIS-GH in Hungary.
• To evaluate the validity and reliability of PROMIS-GH for the Hungarian population.

Main Methods:

• A cross-sectional online survey of 1700 Hungarian adults.
• Analysis of PROMIS-GH v1.2 using Item Response Theory (IRT) models, including unidimensionality, local independence, and monotonicity.
• Convergent validity was assessed using Spearman correlations with SF-36v1, and age- and gender-weighted T-scores were computed.

Main Results:

• IRT assumptions were met, and the graded response model demonstrated acceptable fit for both Global Physical Health (GPH) and Global Mental Health (GMH) subscales.
• PROMIS-GH T-scores showed strong correlations with corresponding SF-36v1 composite scores (GPH: r=0.83, GMH: r=0.71).
• Females and older adults reported significantly lower GPH and GMH T-scores compared to males and younger individuals, respectively.

Conclusions:

• The Hungarian PROMIS-GH is a valid and reliable measure of health status.
• General population reference values for the Hungarian PROMIS-GH were successfully developed.
• These reference values will aid in interpreting patient scores and facilitate international health comparisons.