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Prototheca Infection: A Descriptive Study.
Grace D Cullen1, Zachary A Yetmar1,2, Madiha Fida1,2
1Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Open Forum Infectious Diseases
|June 30, 2023
Summary
Prototheca infections, though rare, can cause skin and soft tissue issues. This study reviews seven cases of Prototheca infections, highlighting clinical presentations and outcomes.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Microbiology
Background:
- Prototheca species are ubiquitous microalgae capable of causing human infections (protothecosis).
- Protothecosis commonly manifests as localized cutaneous or subcutaneous lesions, such as olecranon bursitis.
- Disseminated protothecosis is a rare but serious complication, particularly in immunocompromised individuals.
Purpose of the Study:
- To describe the clinical characteristics and management of Prototheca infections.
- To review the experience of a single institution with seven patients diagnosed with Prototheca infections.
- To contribute to the understanding of Prototheca infection presentations in humans.
Main Methods:
- Retrospective case series analysis.
- Review of medical records for seven patients with confirmed Prototheca infections.
- Analysis of clinical data, treatment, and outcomes.
Main Results:
- Seven cases of Prototheca infections were identified.
- Common presentations included localized soft tissue infections and bursitis.
- Details on specific patient demographics, treatment regimens, and clinical outcomes were documented.
Conclusions:
- Prototheca infections represent a spectrum of disease, from localized to disseminated forms.
- Early recognition and appropriate management are crucial for favorable outcomes in protothecosis.
- Further research is needed to fully elucidate optimal treatment strategies for Prototheca infections.
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