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Urinary Bladder Carcinoma in Females: A Clinico-Pathological Assessment
Rahul Gupta1, Suhail M Khan1, Manik Mahajan2
1Urology, Government Medical College, Jammu, Jammu, IND.
Cureus
|July 3, 2023
Summary
Female bladder cancer, though uncommon, is often high-grade but non-muscle-invasive. Domestic chulha (open wood-burning stove) exposure is identified as a primary risk factor in North India.
Area of Science:
- Urology
- Oncology
- Epidemiology
Background:
- Female bladder cancer is an uncommon and poorly defined entity, with limited literature available, particularly from North India.
- Despite its infrequent diagnosis, understanding the specific characteristics of bladder cancer in women is crucial.
Purpose of the Study:
- To investigate the clinico-pathological profile of bladder cancer in female patients.
- To identify risk factors and outcomes for female bladder cancer in North India.
Main Methods:
- A retrospective observational study was conducted at a tertiary care center in North India.
- Data from 56 female patients diagnosed with bladder cancer between January 2012 and January 2021 were analyzed.
- Key data points included age, disease duration, comorbidities, histopathology, and treatment outcomes.
Main Results:
- Transitional cell carcinoma (TCC) was the predominant diagnosis (55/56 cases).
- Painless hematuria was the most common symptom (80.3%).
- Most cases were non-muscle-invasive (50/55), with a significant proportion being high-grade (31/50).
- Domestic chulha exposure (41.8%) and smoking (20%) were identified as significant risk factors.
Conclusions:
- Female bladder cancer typically presents in the sixth decade of life.
- The majority of cases are high-grade but non-muscle-invasive.
- Domestic chulha exposure is a significant etiological factor for bladder cancer in women in this region.
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