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[Brain abscess as a complication of pulmonary manifestation of HHT]

May Cathleen Müller1, Christina Weiler-Normann1,2, Mathias Meyer3

  • 1Martin Zeitz Centrum für Seltene Erkrankungen, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.

Innere Medizin (Heidelberg, Germany)
|July 7, 2023
PubMed

A 43-year-old female patient with a brain abscess and a complicated clinical course was diagnosed with hereditary haemorrhagic telangiectasia (HHT) at the Martin Zeitz Centre for Rare Diseases in Hamburg, Germany. The brain abscess was caused by pulmonary arteriovenous malformations (AVM), a typical finding in HHT. Patients with cryptogenic brain abscess should be screened for pulmonary AVM and HHT. This case report illustrates the importance of patient history and interdisciplinary exchange in patients with a broad clinical spectrum as well as interdisciplinary treatment in the case of complications of rare diseases.

Keywords:
Arteriovenous malformationGenetic vascular disorderHereditary hemorrhagic telangiectasiaOsler–Rendu–Weber syndromeRare disease

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