Related Experiment Video
Updated: Jul 24, 2025

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
Facial Filler in Facial Paralysis: A Prospective Case Study and Multidimensional Assessment.
Rui Han Liu1, Jenny Yau1, Adeeb Derakhshan1
1Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Facial filler injections effectively improve facial symmetry and patient-reported quality of life in individuals with facial paralysis (FP). This nonsurgical treatment offers significant psychosocial benefits with minimal pain and complications.
Area of Science:
- Plastic Surgery
- Dermatology
- Facial Reanimation
Background:
- Facial filler injections are an emerging nonsurgical option for correcting static asymmetry in facial paralysis (FP).
- Understanding the patient experience is crucial for effective preprocedure counseling and education.
Purpose of the Study:
- To evaluate the patient experience with facial filler injections for facial paralysis.
- To assess the impact of facial fillers on facial symmetry, pain, and quality of life.
Main Methods:
- Prospective study of patients receiving hyaluronic acid filler for FP.
- Assessed patient-reported pain, facial symmetry (VAS), and quality of life (FACE-Q, PHQ-9, EQ5D) pre- and postprocedure.
Main Results:
- Twenty patients completed the study, reporting minimal pain postprocedure.
- Significant improvements were observed in patient-perceived facial symmetry, FACE-Q satisfaction with facial appearance (SFA), and psychosocial distress (PSD).
- Depression (PHQ-9) and anxiety/depression domains of EQ5D scores decreased post-treatment.
Conclusions:
- Facial filler injections for FP are associated with minimal morbidity, including low pain and few complications.
- Hyaluronic acid fillers significantly enhance psychosocial well-being and facial appearance in FP patients.
Related Concept Videos
Facial Feedback Hypothesis
Assessment of Airway, Skin Color, and Use of Accessory Muscles
Introduction
The initial evaluation of a patient's respiratory system...

