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Engineered Living Materials for Advanced Diseases Therapy
Xue Dong1,2, Wei Wu2, Pei Pan3
1Institute for Advanced Studies, Wuhan University, Wuhan, 430072, P. R. China.
Advanced Materials (Deerfield Beach, Fla.)
|July 12, 2023
Summary
Engineered living materials, such as cells and microbes, show promise as biotherapeutics for disease treatment due to their biological activities. This review covers recent advances and future challenges in this rapidly developing field.
Area of Science:
- Biomedical Engineering
- Biotechnology
- Therapeutics
Background:
- Living materials offer unique biological activities for disease treatment.
- Engineered living materials (ELMs) are emerging as novel biotherapeutics.
- Their immunoactivity and tissue targeting properties are key advantages.
Purpose of the Study:
- To summarize recent developments in engineered living materials for biotherapeutics.
- To review various types of living materials used in therapy.
- To discuss future perspectives and challenges in the field.
Main Methods:
- Literature review of engineered living materials.
- Analysis of applications in disease treatment.
- Discussion of current research trends and future directions.
Main Results:
- Diverse living materials (cells, bacteria, viruses, fungi, algae, plants) are engineered as biotherapeutics.
- These materials demonstrate potential in treating various diseases.
- Significant progress has been made in harnessing their biological activities.
Conclusions:
- Engineered living materials represent a promising frontier in biotherapeutics.
- Further research is needed to address challenges and optimize biomedical applications.
- The field holds substantial potential for future therapeutic innovations.
