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Updated: Jul 23, 2025

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Visible-Light-Induced Regioselective Radical Oxo-Amination of Alkenes with O2 as the Oxygen Source
Jiayang Wang1, Baoer Shao2, Haixia Ge1
1School of Life Sciences, Huzhou University, Huzhou, Zhejiang 313002, P. R. China.
Abstract:
An efficient and novel visible-light-induced oxo-amination of terminal alkenes for the construction of α-amino ketones with easily accessible and green O2 as the oxygen source has been developed. The transformation possesses the advantages of operational simplicity, a broad substrate scope, high atom economy, and mild reaction conditions. The mechanistic studies reveal that an energy transfer process probably occurs in the initial stage, and the reaction proceeds via β-scission of the alkoxyl radical species.
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