Cholesterol granuloma of the breast: A case report

Cholesterol granuloma of the breast is a rare entity that can be indistinguishable from cancer on physical exam and imaging. We present the case of a 58-year-old woman who developed a new enhancing mass on high-risk screening magnetic resonance imaging (MRI). Interestingly, this mass developed in the same area as a previously noted benign-appearing inflammatory cyst that had been decreasing in size on MRI and mammogram over many years. Ultrasound-guided biopsy was performed which revealed cholesterol granuloma. We will discuss the nonspecific imaging findings and the characteristic histopathological features that confirm diagnosis.