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Updated: Jul 23, 2025

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Published on: October 3, 2020

Progress in optical sensors-based uric acid detection.

Chiyu Ma¹, Nan Jiang¹, Xianyou Sun¹

¹Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, Zhejiang University, Hangzhou, 310027, China.

Biosensors & Bioelectronics

|July 13, 2023

Summary

This summary is machine-generated.

This review details advancements in optical sensors for detecting abnormal uric acid (UA) levels, crucial for managing diseases like gout. It highlights recent progress and challenges in developing rapid, on-site UA detection methods for home monitoring and community screening.

Keywords:

Nanotechnology On-site devices Optical sensors UA detection

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Published on: July 28, 2021

Area of Science:

Biomedical Engineering
Analytical Chemistry
Optical Sensing Technologies

Background:

Rising prevalence of diseases linked to abnormal uric acid (UA) concentrations necessitates improved detection methods.
Optical sensors offer advantages like simplicity, cost-effectiveness, and electromagnetic interference resistance for UA detection.
On-site UA detection is crucial for home monitoring and rapid community disease screening.

Purpose of the Study:

To systematically review and describe achievements and emerging technologies in UA optical sensors over the last five years.
To analyze the advantages and limitations of various UA optical sensors for on-site applications.
To discuss recent progress in instrumentation and the application of on-site UA detection in body fluids.

Main Methods:

Systematic categorization of UA optical sensor technologies.
Detailed description of sensor achievements and emerging technologies.
Analysis of sensor advantages, limitations, and instrumentation progress.

Main Results:

Highlights significant advancements in UA optical sensor design and performance over the past five years.
Identifies specific benefits and drawbacks of different sensors for practical, on-site use.
Discusses current instrumentation and real-world applications of UA detection in biological samples.

Conclusions:

Optical sensors show great promise for on-site uric acid detection, supporting disease management and screening.
Further research is needed to address existing challenges and optimize sensors for widespread adoption.
This review provides valuable insights for future development in UA optical sensor technology.