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Updated: Jul 23, 2025

Induction and Validation of Cellular Senescence in Primary Human Cells
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Cellular senescence in asthma: from pathogenesis to therapeutic challenges

Rongjun Wan1, Prakhyath Srikaram2, Vineeta Guntupalli2

  • 1Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA; Department of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.

Ebiomedicine
|July 13, 2023
PubMed
Summary

Cellular senescence, the aging of cells, plays a key role in asthma development and progression. Targeting senescent cells with senolytics and senomorphics offers promising new asthma treatment strategies.

Keywords:
AsthmaCellular senescenceSASPSenolyticsSenomorphics

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