2D Gallium Sulfide-Based 1D Photonic Crystal Biosensor for Glucose Concentration Detection

Area of Science:

• Photonics
• Materials Science
• Biomedical Engineering

Background:

• Unidimensional photonic crystals are widely researched for blood glucose measurement.
• Existing biosensors often require labels, complicating detection processes.

Purpose of the Study:

• To propose and analyze two novel 1D photonic crystal biosensor designs using 2D Van der Waals materials.
• To evaluate the performance of these biosensors for blood glucose concentration detection.

Main Methods:

• Numerical analysis using the transfer matrix method.
• Investigation of photonic crystal properties with and without defect layers.
• Assessment of biosensor performance as a function of glucose concentration.

Main Results:

• Two designs utilizing [GaS/Mica] and [GaS/G] multilayers were proposed.
• High sensitivity (832 nm/RIU), figure-of-merit (1.46 × 10^5 RIU^-1), and Q-factor (>10^5) were achieved.
• A minimum limit of detection of 3.4 × 10^-7 RIU was determined, with sensitivity enhanced nearly 5-fold in one design.

Conclusions:

• The proposed 2D Van der Waals material-based photonic crystal biosensors are suitable for sensitive and reliable blood glucose detection.
• These label-free biosensors represent a promising advancement in glucose monitoring technology.
• Further structural modifications can significantly enhance sensor sensitivity.