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Published on: April 7, 2015
Roseomonas Species Bacteremia With Associated Endocarditis and Possible CNS Septic Embolic Phenomenon
Jose A Rodriguez1, Alexis C Gushiken2
1Infectious Diseases, University of Florida, Gainesville, USA.
Abstract:
Rosemonas species has been associated with infections in both immunocompetent and immunocompromised hosts, manifesting as peritonitis, bacteremia, catheter-related bacteremia, endophthalmitis, spondylitis, and endocarditis. Here we present a man in his 60s who was brought to our institution for sudden onset of aphasia, right-sided paresthesia, and new onset tonic-clonic seizure episodes. At presentation, he was found to have severe lactic acidosis, acute kidney failure, bilateral hydronephrosis, elevated prostate-specific antigen (PSA), and an enlarged prostate. Blood cultures obtained on admission later grew Roseomonas species for which he was started on meropenem. A trans-esophageal echocardiogram (TEE) showed multiple very thin mobile densities on the ventricular side of the aortic valve; magnetic resonance imaging (MRI) of the brain revealed an 11 mm acute/subacute hemorrhage. The patient was discharged in stable condition on Ertapenem intravenous therapy for six weeks. Roseomonas mucosa can be a cause of endocarditis. The antimicrobial resistance profile of Roseomonas spp suggests that carbapenems, fluoroquinolones or aminoglycosides are the drugs of choice for Roseomonas infections and that infectious diseases involved in cases of Roseomonas infections should be instituted promptly for proper management.
Insights
Roseomonas species, a rare bacterium, can cause serious infections like endocarditis. Prompt diagnosis and appropriate antibiotic treatment, such as carbapenems, are crucial for managing Roseomonas infections.
Area of Science:
- Infectious Diseases
- Bacteriology
- Cardiology
Background:
- Roseomonas species are increasingly recognized as opportunistic pathogens.
- Infections can manifest in various forms, including bacteremia and endocarditis.
Observation:
- A 60-year-old male presented with neurological symptoms and signs of systemic illness.
- He was diagnosed with lactic acidosis, acute kidney injury, and an 11 mm brain hemorrhage.
- Blood cultures identified Roseomonas species, and transesophageal echocardiogram revealed aortic valve vegetations.
Findings:
- The patient was successfully treated with meropenem and subsequently Ertapenem.
- Roseomonas mucosa was identified as a potential cause of infective endocarditis.
- Antimicrobial susceptibility testing indicated carbapenems, fluoroquinolones, or aminoglycosides as preferred treatments.
Implications:
- This case highlights the importance of considering Roseomonas in patients with severe infections and neurological complications.
- Early recognition and prompt administration of appropriate antimicrobial therapy are vital for favorable outcomes.
- Further research into Roseomonas infections and their management is warranted.
Related Concept Videos
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Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis IV: Nursing Management
Endocarditis III: Medical Management
Acute Pyelonephritis II: Diagnostic Studies and Management
Rheumatic Heart Disease I: Introduction

