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Advances in Monitoring and Prognostication for Lymphoma by Flow Cytometry

Amrit P Singh1, Elizabeth L Courville1

  • 1Department of Pathology, University of Virginia Health, PO Box 800214, Charlottesville, VA 22908, USA.

Clinics in Laboratory Medicine
|July 22, 2023
PubMed

Keywords:
Chronic lymphocytic leukemiaClonalityFlow cytometryImmunophenotypeImmunotherapyLymphomaMRDPrognosis

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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