Related Experiment Video

Updated: Jul 22, 2025

Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
06:02

Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors

Published on: September 13, 2018

6.9K

Morbillivirus: A highly adaptable viral genus

Jane E Libbey1, Robert S Fujinami1

  • 1Department of Pathology, University of Utah School of Medicine, 15 North Medical Drive East, 1100, EEJMRB, Salt Lake City, UT, 84112, USA.

Heliyon
|July 24, 2023
PubMed

Insights

Zoonotic diseases emerge when viruses transmit from animals to humans. Morbilliviruses, ancient pathogens, continue to evolve and could cause future human outbreaks through animal interactions.

Area of Science:

  • Virology
  • Epidemiology
  • Evolutionary Biology

Background:

  • Human history is marked by zoonotic diseases originating from animal virus transmission.
  • Morbilliviruses are ancient pathogens that have evolved over millennia, adapting to new hosts.

Purpose of the Study:

  • To highlight the potential for morbilliviruses to cause future zoonotic diseases in humans.
  • To underscore the ongoing evolutionary dynamics of morbilliviruses.

Main Methods:

  • Review of historical and evolutionary data on morbilliviruses.
  • Analysis of host-switching and adaptation mechanisms in viral pathogens.

Main Results:

  • Morbilliviruses have a long history of transmission and adaptation.
  • Undiscovered or existing morbilliviruses pose a potential threat for future zoonotic spillover events.

Conclusions:

  • Continued vigilance and research into morbilliviruses are crucial for pandemic preparedness.
  • Understanding viral evolution in animal reservoirs is key to preventing future zoonotic diseases.
Keywords:
Canine distemperMeaslesMorbillivirusRinderpest

More Related Videos

Mosquito-Associated Virus Isolation from Field-Collected Mosquitoes06:41

Mosquito-Associated Virus Isolation from Field-Collected Mosquitoes

Published on: August 31, 2022

1.9K
Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation09:50

Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation

Published on: October 27, 2019

7.1K

Related Concept Videos

Viruses with RNA Genomes01:29

Viruses with RNA Genomes

RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
57
Viruses of Archaea01:29

Viruses of Archaea

Archaeal viruses play a crucial role in the ecosystems of extremophilic archaea, particularly those belonging to the phyla Euryarchaeota and Crenarchaeota. By shaping host evolution and facilitating gene transfer, these viruses influence microbial communities and contribute to genetic diversity in extreme environments. The archaea they infect thrive in acidic hot springs and hydrothermal vents characterized by high temperatures and low pH. Archaeal viruses exhibit remarkable structural...
31
Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.5K
Size and Structure of Viral Genomes01:26

Size and Structure of Viral Genomes

Viral genomes exhibit remarkable diversity in size, structure, and composition, influencing their replication strategies and interactions with host cells. These genomes consist of either DNA or RNA and may be linear or circular. Additionally, they can be single-stranded or double-stranded, with each configuration affecting how the virus propagates within a host. RNA viruses, for instance, generally have smaller genomes than DNA viruses, a factor that contributes to their high mutation rates and...
64
Viral Mutations00:36

Viral Mutations

A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
32.4K
Viral Structure00:56

Viral Structure

Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
62.5K