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A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG
Published on: March 7, 2017
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Paediatric Mediastinal Lipoblastoma
Vera Brazão de Carvalho1, João Lopes Dias1, Ana Nunes1
1Centro Hospitalar Universitário Lisboa Central, PT.
Journal of the Belgian Society of Radiology
|July 24, 2023
Insights
Lipoblastoma is a rare, benign fatty tumor that can present as a painful, rapidly growing mass in the mediastinum of young children. Consider lipoblastoma in infants and children under three with such symptoms.
Area of Science:
- Pediatric Oncology
- Surgical Pathology
Background:
- Mediastinal masses in infants and young children can be challenging to diagnose.
- Fatty tumors are uncommon in this location and age group.
Observation:
- A case of a painful, rapidly growing mediastinal mass in a young child is presented.
- The mass was composed of mature and immature lipoblasts, consistent with lipoblastoma.
Findings:
- Lipoblastoma is a rare, benign tumor of infancy and childhood characterized by proliferation of lipoblasts.
- It most commonly occurs in the extremities but can arise in the mediastinum.
Implications:
- Early consideration of lipoblastoma in the differential diagnosis of mediastinal masses in young children is crucial.
- Prompt diagnosis and surgical excision lead to excellent outcomes for lipoblastoma.
Abstract:
Teaching Point: Lipoblastoma should be considered in the differential diagnosis of painful rapidly growing fatty mass within the mediastinum in infants or young children under three years old.

