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Related Experiment Video

Updated: Jul 22, 2025

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG
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Paediatric Mediastinal Lipoblastoma.

Vera Brazão de Carvalho1, João Lopes Dias1, Ana Nunes1

  • 1Centro Hospitalar Universitário Lisboa Central, PT.

Journal of the Belgian Society of Radiology
|July 24, 2023
PubMed
Summary

Lipoblastoma is a rare, benign fatty tumor that can present as a painful, rapidly growing mass in the mediastinum of young children. Consider lipoblastoma in infants and children under three with such symptoms.

Keywords:
ChildrenFat suppressed massHyperechoic massLipoblastomaLipomatous tumorMediastinum

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Area of Science:

  • Pediatric Oncology
  • Surgical Pathology

Background:

  • Mediastinal masses in infants and young children can be challenging to diagnose.
  • Fatty tumors are uncommon in this location and age group.

Observation:

  • A case of a painful, rapidly growing mediastinal mass in a young child is presented.
  • The mass was composed of mature and immature lipoblasts, consistent with lipoblastoma.

Findings:

  • Lipoblastoma is a rare, benign tumor of infancy and childhood characterized by proliferation of lipoblasts.
  • It most commonly occurs in the extremities but can arise in the mediastinum.

Implications:

  • Early consideration of lipoblastoma in the differential diagnosis of mediastinal masses in young children is crucial.
  • Prompt diagnosis and surgical excision lead to excellent outcomes for lipoblastoma.