Naturally Occurring Organohalogen Compounds-A Comprehensive Review

Area of Science:

• Environmental Chemistry
• Natural Products Chemistry
• Biochemistry

Background:

• Organohalogen compounds are widespread in nature, originating from both biological and abiotic sources.
• The documentation of these compounds has grown significantly, from fewer than 25 in 1968 to approximately 8,000 to date.
• This volume represents the third in a trilogy comprehensively cataloging these natural products.

Approach:

• Systematic documentation of naturally occurring organohalogen compounds.
• Inclusion of chemical structures, biological activity, and natural functions.
• Exploration of biohalogenation, biodegradation, and extraterrestrial sources.

Key Points:

• Approximately 8,000 organohalogen compounds have been identified, predominantly containing chlorine or bromine.
• These compounds are produced by a vast array of marine and terrestrial organisms, as well as abiotic processes.
• Extraterrestrial sources of organohalogens have also been identified.

Conclusions:

• Organohalogens are pervasive in the global ecosystem, with diverse origins and functions.
• The study presents a comprehensive overview of known organohalogen compounds, their properties, and their roles.
• Future outlook on organohalogen research, including biodegradation and potential applications, is discussed.