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Prescribing Pattern of Antibiotics among Hospitalized Patients with Urinary Tract Infection
Deepti Shrestha1, Jyotshna Sapkota2, Rekha Poudel1
1Department of Pharmacology, Nepal Medical College, Attarkhel, Kathmandu, Nepal.
Journal of Nepal Health Research Council
|July 25, 2023
Summary
Cephalosporins, particularly ceftriaxone, were the most frequently prescribed antibiotics for hospitalized urinary tract infections (UTIs). Many patients received antibiotics from the "watch" category, indicating a need to monitor antibiotic stewardship for common bacterial infections.
Area of Science:
- Infectious Diseases
- Pharmacology
- Public Health
Background:
- Urinary tract infections (UTIs) are a leading cause of bacterial infections and hospitalization globally.
- UTIs can lead to severe complications such as sepsis.
- Antibiotics and fluid therapy are standard treatments for UTIs.
Purpose of the Study:
- To investigate the antibiotic prescribing patterns for hospitalized patients diagnosed with UTIs.
- To identify the most frequently used antibiotic classes and specific agents.
- To analyze antibiotic use in the context of the AWaRe classification.
Main Methods:
- A descriptive, cross-sectional study was conducted at Nepal Medical College Teaching Hospital.
- Data was collected from January 2022 to April 2022.
- Included were adult patients (≥18 years) admitted with a provisional UTI diagnosis and prescribed antibiotics.
Main Results:
- Cephalosporins were the most prescribed antibiotic group (69.9%), with ceftriaxone being the most common empirical therapy (53.4%).
- Escherichia coli was the predominant pathogen (76.3%).
- A significant majority of patients (78.6%) received antibiotics from the 'watch' category of the AWaRe classification.
Conclusions:
- Cephalosporins, especially ceftriaxone, dominate antibiotic prescribing for hospitalized UTIs.
- Antibiotic use skewed towards the 'watch' group in the AWaRe classification.
- Findings highlight the need for robust antibiotic stewardship programs to optimize UTI treatment.
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