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Cardiovascular and pulmonary activity of platelet-activating factor (PAF-acether) and its derivatives
Pharmacological Research Communications
|June 1, 1986
Abstract:
Stereoselective synthesis and biological properties of PAF-acether, its enantiomer and some analogues of both are reported. The results clearly indicate that the ONIUM SIZE and SHAPE of the various compounds tested are important in determining guinea-pig bronchoconstriction and human platelet aggregation.