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Related Concept Videos

Regional Terms01:12

Regional Terms

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Regional terms describe anatomy by dividing the body parts into different regions that contain structures involved in contributing similar functions. Using these terms helps increase the accurate description and identification of the particular region of interest or region affected by the disease.
Primarily, the human body has two major regions, the axial and appendicular regions. The axial region comprises regions from the head to the abdomen and makes up the central body axis. In contrast,...
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Pain01:20

Pain

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Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
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Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

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Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
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Analgesia and Pain Management01:25

Analgesia and Pain Management

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Abdominal Regions and Quadrants01:19

Abdominal Regions and Quadrants

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To promote clear communication, for instance, about the location of a patient's abdominal pain or a suspicious mass, anatomists and clinicians typically use imaginary lines to categorize the abdominopelvic cavity into either four quadrants or nine regions to identify organs in the cavity.
The simpler quadrants approach, which is more commonly used in medicine, subdivides the cavity with one horizontal and one vertical line that intersects at the patient's umbilicus (navel). The four...
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Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
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Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

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Complex regional pain syndrome.

Micayah Mills1, Christopher M Howell

  • 1At the time this article was written, Micayah Mills was a student in the PA program at Kettering (Ohio) College. She now practices at Kettering Health Brain and Spine Center. Christopher M. Howell is an associate professor and program director of the PA program at Miami University in Oxford, Ohio. The authors have disclosed no potential conflicts of interest, financial or otherwise.

JAAPA : Official Journal of the American Academy of Physician Assistants
|July 26, 2023
PubMed
Summary
This summary is machine-generated.

Complex regional pain syndrome (CRPS) is a chronic pain condition affecting a localized body area. Predicting its risk and course is challenging, necessitating holistic patient care for improved quality of life.

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Area of Science:

  • Pain Medicine
  • Neurology
  • Rehabilitation Medicine

Background:

  • Complex regional pain syndrome (CRPS), previously known as reflex sympathetic dystrophy (RSD), is a chronic pain condition.
  • It involves altered peripheral and central pain perception in a specific body region.
  • The multifactorial nature of CRPS presents challenges in predicting disease risk and clinical trajectory.

Purpose of the Study:

  • To highlight the complexities in predicting CRPS risk and clinical course.
  • To emphasize the importance of prompt diagnosis and treatment.
  • To advocate for a holistic approach to patient management in CRPS.

Main Methods:

  • Review of existing literature on CRPS pathophysiology and risk factors.
  • Analysis of clinical challenges in predicting disease progression.
  • Discussion of holistic patient care strategies.

Main Results:

  • CRPS involves significant alterations in pain perception.
  • Predicting the exact risk factors and clinical course of CRPS remains difficult.
  • Holistic patient assessment is crucial for effective management.

Conclusions:

  • Early diagnosis and prompt treatment are vital for CRPS patients.
  • A comprehensive approach considering overall health and function is essential.
  • Improving quality of life requires integrated patient care strategies.