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Updated: Jul 21, 2025

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
Complex regional pain syndrome
Micayah Mills1, Christopher M Howell
1At the time this article was written, Micayah Mills was a student in the PA program at Kettering (Ohio) College. She now practices at Kettering Health Brain and Spine Center. Christopher M. Howell is an associate professor and program director of the PA program at Miami University in Oxford, Ohio. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Abstract:
Complex regional pain syndrome (CRPS), formerly called reflex sympathetic dystrophy (RSD), is a chronic pain phenomenon associated with an alteration in peripheral and central pain perception in a localized body region. Because of the many risk factors associated with this phenomenon, the true nature of the disease risk and clinical course are a challenge to predict. After the diagnosis is confirmed and treatment is provided promptly, clinicians must consider patient health and function holistically to foster improvement in overall quality of life.
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