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Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells

Nadia M E Ayad1,2, Johnathon N Lakins2, Ajinkya Ghagre3

  • 1Graduate Program in Bioengineering, University of California, San Francisco and University of California Berkeley, San Francisco, CA 94143, USA; Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.

Biorxiv : the Preprint Server for Biology
|July 28, 2023
PubMed

Keywords:
Wnt signalingcytoskeletal tensiongastrulationgastruloidshuman embryonic stem cellsmechanical forcesmechanotransductionmesoderm specificationtraction force microscopy (TFM)β-catenin

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