Efficacy of implementing a BRCA screening protocol in primary care

Area of Science:

• Genetics and Genomics
• Oncology
• Preventive Medicine

Background:

• Breast and ovarian cancers pose significant health risks, with mutations in BRCA1 and BRCA2 genes substantially elevating susceptibility.
• Early detection through screening and genetic counseling is crucial for managing hereditary cancer risk.
• Healthcare provider knowledge gaps regarding BRCA mutations can impede timely screening and referrals.

Purpose of the Study:

• To enhance healthcare provider knowledge concerning BRCA1 and BRCA2 mutations.
• To promote the utilization of BRCA screening tools and increase genetic referrals for at-risk patients.
• To evaluate the impact of targeted education on provider confidence, screening practices, and referral rates.

Main Methods:

• An Institutional Review Board-approved educational intervention was delivered to healthcare providers.
• Training included a standardized webinar and multimodal educational materials focusing on BRCA mutations, screening, and referral protocols.
• Data on provider knowledge, confidence, BRCA screenings, and genetic referrals were collected via the electronic health record (EHR).

Main Results:

• Eight providers (five nurse practitioners, three medical doctors) completed the training.
• A total of 56 patients underwent BRCA screening, leading to four referrals for genetic counseling.
• The educational program demonstrably enhanced provider knowledge, increased the use of screening tools, and improved genetic referral rates.

Conclusions:

• Targeted education effectively improves healthcare provider understanding and application of BRCA mutation screening and referral pathways.
• Enhanced provider knowledge and confidence correlate with increased patient screenings and timely genetic referrals, facilitating early detection of hereditary cancers.
• Integration of EHR monitoring is valuable for tracking the impact of educational initiatives on clinical practice and patient outcomes.