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Preferred Mode of Therapy Among Patients in Rheumatoid Arthritis Saudi Database: A Cross-Sectional Study
Rahaf I Bukhari1, Rasha Alamr2, Ranin A Alsindi2
1Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, SAU.
Cureus
|July 31, 2023
Summary
Rheumatoid arthritis patients overwhelmingly prefer oral medications over injections. Ease of administration is key, though adherence challenges exist for oral rheumatoid arthritis (RA) treatments.
Area of Science:
- Rheumatology
- Patient-reported outcomes
- Pharmacotherapy
Background:
- Limited understanding of patient preferences for rheumatoid arthritis (RA) treatment modalities.
- Need to identify preferred routes of administration among RA patients.
Purpose of the Study:
- Determine the most favored therapy mode (oral, subcutaneous, intravenous) for RA patients.
- Understand the rationale behind patient choices for RA treatment routes.
Main Methods:
- Cross-sectional, nationwide qualitative study involving 308 RA patients.
- Interviews assessed preferred therapy mode and reasons for choice.
- A 10-point allocation system evaluated determining factors for therapy preference.
Main Results:
- Oral route was the most preferred RA treatment (73.3%), followed by subcutaneous injection (19.5%) and IV infusion (7.3%).
- Ease of drug administration was the primary reason for preferring oral therapy (63.2%).
- Difficulty with adherence and swallowing pills were key concerns for avoiding oral RA treatments.
Conclusions:
- The oral route is the most preferred RA treatment modality in this cohort.
- Shared decision-making between patients and physicians is crucial for RA management.
- Patient preferences significantly influence the choice of RA therapy administration route.
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