Related Experiment Video
Updated: Jul 20, 2025
Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
STAR procedure becomes SAFER: First-in-man case series of a new antegrade dissection re-entry technique
Mauro Carlino1, Barry F Uretsky2, Lorenzo Azzalini3
1Cardio-Thoracic-Vascular Department, Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Introduction:
Antegrade dissection and re-entry (ADR) is an integral part of the hybrid algorithm, which has allowed for improved outcomes in chronic total occlusion (CTO) coronary intervention (PCI).
Methods:
A new ADR method, Subintimal Antegrade FEnestration and Re-entry (SAFER), is described. The results of a first-in-man series are presented.
Results:
SAFER was performed on seven consecutive patients with angiographic and clinical success in all patients.
Conclusions:
This first-in-man study has shown that the SAFER technique is feasible and effective with the possibility of improving the antegrade PCI CTO success rate.
