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Updated: Jul 20, 2025

Biofunctionalization of Magnetic Nanomaterials

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

Nanoparticles with transformable physicochemical properties for overcoming biological barriers.

Qianqian Lu¹, Hongyue Yu¹, Tiancong Zhao¹

¹Department of Chemistry, Laboratory of Advanced Materials, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Chemistry for Energy Materials (2011-iChEM), Fudan University, Shanghai 200433, P. R. China. zhao_tc@fudan.edu.cn.

|August 1, 2023

Summary

Nanomedicines with transformable physicochemical properties offer enhanced targeting for advanced therapeutics. This review details how adaptable nanomaterials overcome biological barriers for improved drug delivery.

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Last Updated: Jul 20, 2025

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Area of Science:

Biomedical Engineering
Materials Science
Drug Delivery

Background:

Nanomedicines show promise for advanced therapeutics but face challenges in precise targeting and delivery.
Biological barriers impede nanoparticle transport, limiting the efficacy of conventional nanomedicines.

Purpose of the Study:

To review recent advancements in nanomedicines with transformable physicochemical properties.
To analyze biological barriers and the design strategies for adaptable nanomaterials.

Main Methods:

Summarizing research on nanomedicines with switchable size, charge, and shape.
Discussing emerging transformable properties like mobility, roughness, and mechanical characteristics.

Main Results:

Physicochemical transformability allows nanomedicines to adapt to biological environments.
Adaptable properties enable overcoming biological barriers and maximizing delivery efficiency.

Conclusions:

Nanomedicines with transformable physicochemical properties represent a significant step forward in drug delivery.
Further research is needed to address the prospects and challenges of these advanced nanomaterials.