Palpebral asymmetry and hyperthyroidism. Two cases in connection with Graves' disease

Area of Science:

• Ophthalmology
• Endocrinology

Background:

• Eyelid retraction and ptosis have diverse etiologies.
• Thyroid-related eye disease is a common cause of such changes.
• Diagnosis is typically straightforward in thyrotoxic patients but can be complex in euthyroid individuals, especially with asymmetric presentations.

Observation:

• This report details two patients presenting with ptosis on one side and eyelid retraction on the contralateral side.
• Both patients had an underlying thyroid disorder.

Findings:

• Thyroid dysfunction can manifest as asymmetric eyelid abnormalities, including ptosis and retraction.
• Euthyroid status does not preclude thyroid-related eyelid changes, complicating diagnosis.

Implications:

• Increased awareness of thyroid eye disease is crucial for diagnosing eyelid abnormalities, even in euthyroid patients.
• Asymmetric eyelid findings warrant thorough investigation for underlying systemic conditions like thyroid dysfunction.
• Early diagnosis and management of thyroid eye disease can prevent further ocular complications.