Related Experiment Video
Updated: Jul 2, 2026

06:47
Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique
Published on: September 20, 2011
37.4K
Hybrid Nanoplatforms Comprising Organic Nanocompartments Encapsulating Inorganic Nanoparticles for Enhanced Drug
Fatih Yanar1, Dario Carugo2, Xunli Zhang3
1Department of Molecular Biology and Genetics, Bogazici University, 34342 Istanbul, Türkiye.
Molecules (Basel, Switzerland)
|August 12, 2023
Summary
Hybrid nanomaterials combine organic and inorganic nanoparticles for improved drug delivery and diagnostics. These advanced systems offer enhanced stability, bioavailability, and reduced toxicity for biomedical applications.
Area of Science:
- Nanomedicine
- Materials Science
- Biotechnology
Background:
- Organic and inorganic nanoparticles (NPs) possess unique properties for diagnostics and therapy.
- Hybrid nanomaterials integrate inorganic NPs within organic nanocompartments (e.g., liposomes, micelles).
- These systems are explored for in vivo drug delivery and theranostic applications.
Purpose of the Study:
- To review recent advancements in hybrid nanoparticulate systems.
- To highlight the use of organic nanocompartments encapsulating inorganic NPs.
- To focus on applications in drug delivery, bioimaging, and theranostics.
Main Methods:
- Literature review of hybrid nanomaterials.
- Analysis of organic nanocompartment and inorganic NP integration.
- Evaluation of applications in nanomedicine.
Main Results:
- Hybrid systems enhance NP stability, bioavailability, and reduce toxicity.
- Synergistic interactions between organic and inorganic components improve therapeutic efficacy.
- Platforms enable multifunctional agents for bioimaging and targeted delivery.
Conclusions:
- Hybrid nanoparticulate systems show significant potential for clinical applications.
- These materials offer improved performance over individual components.
- Further development holds promise for advanced nanomedicine solutions.
Keywords:
bioimagingdrug deliveryencapsulationhybrid nanoparticlesinorganic nanoparticlesorganic nanoparticlesMore Related Videos
Related Concept Videos
Modified-Release Drug Delivery Systems: Site-Targeted
Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

