Biogenic Synthesis of Silver Nanoparticles and Their Diverse Biomedical Applications
Xiaokun Jiang1,2, Shamma Khan1, Adam Dykes1
1Faculty of Engineering and Physical Sciences, University of Southampton, Southampton SO17 1BJ, UK.
Molecules (Basel, Switzerland)
|August 14, 2025
Summary
Biogenic synthesis offers sustainable silver nanoparticles (AgNPs) for diverse biomedical uses. This review explores eco-friendly methods, applications, and future directions for these versatile nanoparticles.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Green Chemistry
Background:
- Biogenic nanoparticles (NPs) present sustainable solutions for biomedical applications.
- Silver nanoparticles (AgNPs) exhibit unique properties and therapeutic potential.
- Existing synthesis methods often lack sustainability and scalability.
Purpose of the Study:
- To review biogenic synthesis methods for AgNPs.
- To explore the influence of reaction conditions on AgNP characteristics.
- To discuss the biomedical applications and future prospects of biogenic AgNPs.
Main Methods:
- Literature review of microbial, plant-based, and biomolecule-assisted AgNP synthesis.
- Analysis of reaction parameters (pH, temperature, media composition).
- Examination of AgNP formation mechanisms and structure-property relationships.
Main Results:
- Biogenic synthesis, particularly microbial, offers eco-friendly and scalable AgNP production.
- Reaction conditions significantly impact AgNP size, shape, and functionality.
- Biogenic AgNPs demonstrate potential in antibacterial, anticancer, drug delivery, and theranostic applications.
Conclusions:
- Biogenic AgNPs are a promising sustainable platform for advanced biomedical solutions.
- Further research is needed to address challenges in reproducibility, scalability, and biosafety.
- Tailored engineering of AgNPs will drive next-generation therapeutic and diagnostic tools.
