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Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
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Related Experiment Video

Updated: Jul 19, 2025

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Systemic multiple myeloma and colonic abnormalities.

Katarzyna M Pawlak1, Kareem Khalaf1,2, Klaus Mönkemüller3,4,5

  • 1Division of Gastroenterology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

Videogie : an Official Video Journal of the American Society for Gastrointestinal Endoscopy
|August 14, 2023
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Summary

This study observed colonic abnormalities in patients with systemic multiple myeloma. These findings highlight potential gastrointestinal complications associated with this blood cancer.

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Area of Science:

  • Gastroenterology
  • Oncology
  • Hematology

Background:

  • Systemic multiple myeloma is a cancer of plasma cells.
  • Gastrointestinal manifestations of multiple myeloma are not well-documented.

Purpose of the Study:

  • To document and describe colonic abnormalities in patients diagnosed with systemic multiple myeloma.
  • To raise awareness of potential gastrointestinal involvement in multiple myeloma.

Main Methods:

  • Review of video recordings of colonoscopies performed on patients with systemic multiple myeloma.
  • Identification and categorization of observed colonic abnormalities.

Main Results:

  • Multiple myeloma patients exhibited various colonic abnormalities.
  • Specific findings included [details to be added based on full study].

Conclusions:

  • Colonic abnormalities can occur in systemic multiple myeloma.
  • Further research is warranted to understand the clinical significance and management of these findings.