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Medication-induced hair loss: An update
Lina Alhanshali1, Michael Buontempo2, Jerry Shapiro3
1Department of Dermatology, SUNY Downstate College of Medicine, Brooklyn, New York.
Journal of the American Academy of Dermatology
|August 17, 2023
Summary
Many medications, including cytotoxic agents, biologics, and immunomodulating agents, can cause drug-induced hair loss (alopecia). This article reviews the diagnosis and management of this common side effect, highlighting recently identified culprits.
Area of Science:
- Dermatology
- Pharmacology
- Oncology
Background:
- Drug-induced hair loss, or alopecia, is a significant adverse effect associated with various therapeutic agents.
- Commonly implicated drug classes include cytotoxic chemotherapy, biologics, and immunomodulating agents.
Purpose of the Study:
- To provide a comprehensive overview of drug-induced alopecia.
- To discuss the diagnostic approaches and current management strategies.
- To highlight recently identified drugs associated with hair loss.
Main Methods:
- Literature review of drug-induced alopecia.
- Analysis of recently published studies and clinical data.
- Synthesis of diagnostic criteria and management guidelines.
Main Results:
- A wide range of medications can precipitate hair loss.
- Early diagnosis and appropriate management are crucial for patient outcomes.
- Emerging drug classes are increasingly recognized as causes of alopecia.
Conclusions:
- Drug-induced hair loss necessitates careful consideration in clinical practice.
- Understanding the spectrum of causative agents and management options is essential for healthcare providers.
- Further research is needed to elucidate mechanisms and develop targeted therapies.
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