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Related Experiment Video

Updated: Jul 18, 2025

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Krill's Disease: A Newer Management Option.

Sarang P Lambat1, Vinay B Nangia1, Prabhat V Nangia2

  • 1Vitreoretinal Services, Suraj Eye Institute, Nagpur, India.

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Summary

Acute retinal pigment epitheliitis (ARPE) is a self-limiting eye condition. This case report suggests that intravenous methylprednisolone (IVMP) may rapidly resolve ARPE symptoms.

Keywords:
Intravenous MethylprednisoloneKrill's DiseaseAcute Retinal Pigment Epithelitis

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Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Medical Case Reports

Background:

  • Acute retinal pigment epitheliitis (ARPE), also known as Krill's disease, is a self-limiting retinal condition.
  • Currently, there is no specific established treatment for ARPE.

Observation:

  • A young female presented with a few days history of scotoma in her right eye.
  • Clinical examination and imaging were consistent with a diagnosis of ARPE.
  • The patient was treated with intravenous methylprednisolone (IVMP).

Findings:

  • Spectral-domain optical coherence tomography (SD-OCT) revealed a reduction in lesion hyperreflectivity and height by day 3 post-IVMP.
  • Near-total resolution of the ARPE lesion was observed by day 5 post-IVMP.

Implications:

  • This case suggests that IVMP may be an effective treatment for rapidly resolving ARPE.
  • Further studies are warranted to confirm the efficacy of IVMP in ARPE management.