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EagleC Explorer: A desktop application for interactively detecting and visualizing SVs and enhancer hijacking on Hi-C
Biorxiv : the Preprint Server for Biology
|August 23, 2023
Summary
EagleC Explorer is new desktop software for analyzing cancer genomes using Hi-C data. It helps visualize structural variations and enhancer hijacking events, aiding cancer research.
Area of Science:
- Genomics
- Bioinformatics
- Cancer Research
Background:
- Hi-C technology is valuable for detecting structural variations (SVs) and enhancer hijacking.
- Existing tools lack intuitive visualization and detection capabilities for SVs and enhancer hijacking on personal computers.
- This gap hinders the widespread adoption of Hi-C for cancer genome discovery.
Conclusions:
- EagleC Explorer addresses the need for accessible tools in cancer genomics research.
- The software empowers researchers to intuitively discover and analyze SVs and enhancer hijacking events.
- It enhances the utility of Hi-C data for advancing cancer studies and facilitating novel discoveries.
