Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aging01:26

Aging

86
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
86
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

2.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.1K
Erikson's Theory on Socioemotional Development during Adulthood01:27

Erikson's Theory on Socioemotional Development during Adulthood

141
Erik Erikson's theory of psychosocial development outlines a series of stages through which individuals progress across the lifespan. Each stage involves a psychosocial conflict that significantly influences personal growth and well-being. Three key stages — intimacy versus isolation, generativity versus stagnation, and integrity versus despair — highlight the developmental challenges faced in adulthood.
Intimacy Versus Isolation in Early Adulthood
Individuals in early...
141
Kubler Ross's Stages of Dying01:21

Kubler Ross's Stages of Dying

118
Elisabeth Kübler-Ross significantly advanced psychology's understanding of the process of dying with her influential book, On Death and Dying (1969). She focused on studying terminally ill individuals and outlined five stages commonly experienced when coping with death: denial, anger, bargaining, depression, and acceptance.
In denial, individuals reject the reality of their condition, often thinking, "This isn't true; I feel fine," as a way to protect themselves from...
118
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

94
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
94
Ethical Dilemmas II01:30

Ethical Dilemmas II

1.1K
Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Two-Dimensional CT Tumor Measurement Predicts Pathological Response and Prognosis After Neoadjuvant DCF Therapy in Esophageal Squamous Cell Carcinoma.

Cancers·2026
Same authorSame journal

Brain-computer interfaces: A lifeline for paralysis or a Pandora's box for humanity?

Bioscience trends·2026
Same author

Verification of the value of optimization of the medication-related clinical decision support system in China, a hospital-based study.

JAMIA open·2026
Same author

Efficacy of a Novel Ablation Index Algorithm for Cavotricuspid Isthmus Ablation Using a Flexible-Tip Ablation Catheter.

Journal of arrhythmia·2026
Same author

Trifluridine/tipiracil enhances radiation-induced abscopal effects and augments PD-1 blockade in gastric cancer.

Scientific reports·2026
Same author

Characteristic pathological findings of achalasia behind unresectable esophageal cancer with pathological complete response after chemotherapy: a case report and literature review.

BMC gastroenterology·2026
Same journal

Stem cell-derived extracellular vesicles for rare diseases: A clinical‑bottleneck‑to‑mechanism framework for translation.

Bioscience trends·2026
Same journal

Clinical translation and accessibility of brain-computer interfaces: From technology development to clinical application.

Bioscience trends·2026
Same journal

Early post-reperfusion neutrophil dynamics after liver transplantation: Association with graft size.

Bioscience trends·2026
Same journal

Moving long-term care insurance upstream: A geriatric-syndrome-oriented framework for healthy aging in China.

Bioscience trends·2026
Same journal

From pilot programs to nationwide implementation: Reform of China's long-term care insurance in an aging society.

Bioscience trends·2026
See all related articles

Related Experiment Video

Updated: Jul 18, 2025

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
05:53

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty

Published on: July 24, 2013

16.6K

Facing frailty: Are you ready?

Tetsuya Asakawa1, Takashi Karako2,3

  • 1Institute of Neurology, National Clinical Research Center for Infectious Diseases, the Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.

Bioscience Trends
|August 23, 2023
PubMed
Summary
This summary is machine-generated.

Defining frailty is crucial for public health. Future research needs objective tools and clinical trials to establish the clinical value of interventions for this aging-related condition.

Keywords:
assessment toolsclinical outcomefrailtypopulation agingrehabilitation

More Related Videos

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
04:00

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

575
Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
07:27

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

10.3K

Related Experiment Videos

Last Updated: Jul 18, 2025

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
05:53

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty

Published on: July 24, 2013

16.6K
Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
04:00

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

575
Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
07:27

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

10.3K

Area of Science:

  • Gerontology
  • Public Health
  • Clinical Medicine

Background:

  • Frailty is an aging-related condition with significant public health implications.
  • A lack of consensus on its definition hinders research and clinical application.
  • Existing studies lack robust evidence on frailty's clinical value in preventing severe illness.

Purpose of the Study:

  • To analyze existing challenges in frailty research.
  • To propose strategies for improving future frailty investigations.

Main Methods:

  • Review of previous frailty studies.
  • Identification of limitations in current frailty research methodologies.

Main Results:

  • Significant inconsistencies exist in the definition and measurement of frailty.
  • Current evidence on the clinical utility of frailty interventions is insufficient.

Conclusions:

  • A standardized definition of frailty is the primary requirement.
  • Objective measurement tools leveraging new technologies are essential.
  • Well-designed clinical trials are needed to validate interventions for frailty.