[Changes in the concentration of pilocarpine eyedrops in normal storage]

The accommodative myopia induced by pilocarpine eye drops served as an indicator for the pharmacological activity. In a case of pigment glaucoma a reproducible 50% decay of the accomodative myopia was measured in the course of two weeks after opening an original bottle. Correlated to the reduction in accommodative myopia, a rise in intraocular pressure was observed. This may be due to an active principle decay caused by moderate temperatures.