Related Experiment Video
Updated: Jul 18, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
How AI can learn from the law: putting humans in the loop only on appeal
I Glenn Cohen1,2, Boris Babic3, Sara Gerke4,5
1The Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics at Harvard Law School, The Project on Precision Medicine, Artificial Intelligence, and the Law (PMAIL), Cambridge, MA, USA. igcohen@law.harvard.edu.
Integrating human expertise into artificial intelligence (AI) and machine learning (ML) decisions is crucial. An appeals process allows human experts to review AI/ML judgments, enhancing accuracy and efficiency.
Area of Science:
- Computer Science
- Medical Ethics
- Public Policy
Background:
- Growing use of AI/ML in decision-making.
- Public reluctance to fully automate expert judgment.
- Need for effective human-AI/ML collaboration.
Purpose of the Study:
- Propose a model for integrating human expertise with AI/ML judgments.
- Address the conflict between algorithmic decisions and human oversight.
- Enhance the efficiency and accuracy of AI/ML systems.
Main Methods:
- Analogy with judicial appellate processes.
- Focus on human expert review of initial AI/ML decisions.
- Application to medical AI/ML use cases.
Main Results:
- Human-in-the-loop via appeals is an efficient labor division.
- Humans provide nuanced reasoning and case-specific insights.
- AI/ML error correction is achieved while maintaining efficiency.
Conclusions:
- Appeals-based human review effectively combines AI/ML efficiency with human expertise.
- This model is applicable across various domains, especially medicine.
- Balances automated decision-making with essential human oversight.
Related Concept Videos
Non-equilibrium in the Cell
Purposive Learning
Avoidance Learning and Learned Helplessness
Avoidance learning occurs when an organism learns that a specific behavior can prevent an unpleasant outcome. For example, a student who receives a bad grade may start studying harder to avoid future poor grades. This behavior persists even when the negative outcome is no longer present. Avoidance learning is powerful because it maintains behavior in the absence of the...
Observational Learning
Cognitive Learning
E. C. Tolman's theory of purposive behavior emphasizes that much behavior is goal-directed. He argued that to understand behavior, we must look at the entire sequence of actions leading to a goal. For instance, high school students study hard, not just due to past reinforcement but also to achieve the goal of getting into a good college.
Tolman introduced the idea that behavior is influenced by...
Law of Effect
Edward Thorndike's foundational work involved studying learning in animals, particularly using puzzle...

