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A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS
Published on: February 21, 2011
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Digital Alternative Communication for Individuals with Amyotrophic Lateral Sclerosis: What We Have
Felipe Fernandes1, Ingridy Barbalho1, Arnaldo Bispo Júnior1
1Laboratory of Technological Innovation in Health (LAIS), Federal University of Rio Grande do Norte (UFRN), Natal 59010-090, Brazil.
Journal of Clinical Medicine
|August 26, 2023
Summary
This review explores eye-image-based Human-Computer Interaction (HCI) for Augmentative and Alternative Communication (AAC) in Amyotrophic Lateral Sclerosis (ALS). Findings show feasibility but highlight challenges in real-world application for ALS patients.
Area of Science:
- Biomedical Engineering
- Rehabilitation Technology
- Assistive Technology
Background:
- Amyotrophic Lateral Sclerosis (ALS) progressively impairs motor function and communication.
- Augmentative and Alternative Communication (AAC) tools are vital for maintaining autonomy and quality of life in ALS patients.
- Eye-image-based Human-Computer Interaction (HCI) offers a promising avenue for AAC.
Purpose of the Study:
- To systematically review eye-image-based HCI approaches for AAC in individuals with ALS.
- To identify and analyze existing strategies and computational techniques.
- To assess the feasibility and challenges of these technologies.
Main Methods:
- Systematic Literature Review (2010-2021) across six major scientific repositories.
- Inclusion/exclusion criteria and quality assessment applied to primary studies.
- Analysis of four identified HCI strategies: Eye-Gaze, Eye-Blink, Eye-Tracking, and Hybrid.
Main Results:
- Twenty-five primary studies were evaluated, revealing four main HCI strategies.
- Eye-Gaze (36%), Eye-Blink (28%), Eye-Tracking (28%), and Hybrid (8%) were the identified approaches.
- Computational techniques and development workflows were documented, demonstrating feasibility in control groups.
Conclusions:
- Eye-image-based HCI shows potential for developing AAC solutions for ALS.
- Lack of experimental testing in ALS patients indicates challenges in scalability, efficiency, and usability.
- Despite challenges, advancements offer a promising future for improving the lives of individuals with ALS.

