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Updated: Jul 18, 2025
Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
Published on: August 8, 2022
Fabrication and Characterization of Porous Diopside/Akermanite Ceramics with Prospective Tissue Engineering
Adrian Ionut Nicoara1,2,3, Andrada Elena Alecu1,3, Gabriel-Costin Balaceanu1
1Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.
Abstract:
Tissue engineering requires new materials that can be used to replace damaged bone parts. Since hydroxyapatite, currently widely used, has low mechanical resistance, silicate ceramics can represent an alternative. The aim of this study was to obtain porous ceramics based on diopside (CaMgSi2O6) and akermanite (Ca2MgSi2O7) obtained at low sintering temperatures. The powder synthesized by the sol-gel method was pressed in the presence of a porogenic agent represented by commercial sucrose in order to create the desired porosity. The ceramic bodies obtained after sintering thermal treatment at 1050 °C and 1250 °C, respectively, were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR) to determine the chemical composition. The open porosity was situated between 32.5 and 34.6%, and the compressive strength had a maximum value of 11.4 MPa for the samples sintered at 1250 °C in the presence of a 20% wt porogenic agent. A cell viability above 70% and the rapid development of an apatitic phase layer make these materials good candidates for use in hard tissue engineering.
