A Review on Pretreatment and Analysis Methods of Polyether Antibiotics in Complex Samples
Xin-Wei Wei1, Yuan Zhang1, Yu Zhou2
1School of Pharmacy, China Medical University, Shenyang, China.
Critical Reviews in Analytical Chemistry
|August 30, 2023
Summary
Polyether antibiotics (PAs) residues in food pose health risks. This review details advanced pretreatment and detection methods for accurate PA analysis, ensuring food safety.
Area of Science:
- Food Chemistry
- Analytical Chemistry
- Veterinary Pharmacology
Background:
- Polyether antibiotics (PAs) are crucial for treating coccidiosis in livestock.
- Residues of PAs in food products present significant human health risks.
- Accurate and reliable analytical methods are essential for monitoring PA residues.
Purpose of the Study:
- To review and critically evaluate pretreatment and detection methods for polyether antibiotics (PAs) in various food matrices.
- To cover advancements in analytical techniques for PAs since 2010.
- To discuss the advantages and disadvantages of different methods and propose future research directions.
Main Methods:
- Literature review of pretreatment techniques including dispersive liquid-liquid microextraction, solid-phase extraction, QuEChERS, and supercritical fluid extraction.
- Review of detection methods, primarily liquid chromatography coupled with various detectors and sensors.
- Analysis of methods applied to diverse sample matrices.
Main Results:
- A comprehensive overview of established and emerging methods for PA analysis.
- Discussion on the efficacy, limitations, and applicability of different extraction and detection techniques.
- Identification of trends and challenges in the field of PA residue analysis.
Conclusions:
- Robust and accurate analytical methods are vital for ensuring the safety of food products concerning PAs.
- The review highlights the progress in analytical methodologies for PA detection.
- Future research should focus on developing more sensitive, rapid, and cost-effective methods.
