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Cell-based Therapy for Heart Failure in Rat: Double Thoracotomy for Myocardial Infarction and Epicardial Implantation of Cells and Biomatrix
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[Management of heart failure at the CHU the National Reference of Ndjamena/Chad]

Abdel-Madjid Zakaria Zakaria1, Oumar Mahamat-Azaki1, Yaya Kichiné Mahamat1

  • 1Service de Cardiologie du CHU de la Référence Nationale. BP : 130 Ndjamena, Tchad.

Annales De Cardiologie Et D'Angeiologie
|August 30, 2023
PubMed

Insights

Heart failure (HF) is a significant public health issue. This study in Chad found hypertension, valvular, and ischemic heart disease as primary causes, with high diuretic and ACE inhibitor use and a 9% mortality rate.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Context:

  • Heart failure (HF) presents a substantial global health challenge.
  • This study was conducted in the cardiology department of a national referral university hospital in N'Djamena, Chad.

Purpose:

  • To investigate the clinical, etiological, therapeutic, and evolutionary profiles of heart failure patients.
  • To understand the prevalence and characteristics of heart failure in a specific African setting.

Summary:

  • Heart failure constituted 30.84% of cardiovascular hospitalizations.
  • The average patient age was 52 ± 34 years, with a slight female predominance (50.7%).
  • Hypertensive, valvular, and ischemic heart disease were the leading causes. Loop diuretics, ACE inhibitors, and beta-blockers were commonly prescribed, and the in-hospital mortality rate was 9%.

Impact:

  • Provides crucial data on heart failure epidemiology in Chad.
  • Highlights the importance of managing hypertension and valvular diseases for HF prevention.
  • Informs clinical practice and public health strategies for heart failure management in similar regions.
Abstract

Keywords:
AméliorationHeart failureImprovementInsuffisance cardiaqueManagementNdjamena/ChadNdjamena/TchadPlateau techniquePrise en chargeTechnical platform

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