Synthesis and Characterization of Naringin Functionalized Nano-Hydroxyapatite for Bone Tissue Engineering

Area of Science:

• Biomaterials Science
• Nanotechnology
• Regenerative Medicine

Background:

• Bone is a complex nanocomposite essential for skeletal structure and function.
• Bone grafting is a surgical technique to enhance bone regeneration in dentistry and orthopedics.
• Standard bone repair therapies present limitations, driving the need for advanced nanomaterials.

Purpose of the Study:

• To synthesize and characterize Naringin (NA) functionalized hydroxyapatite nanoparticles (n-HA).
• To evaluate the potential of NA-functionalized n-HA as a bone regenerative material.

Main Methods:

• Synthesis of Naringin (NA) functionalized hydroxyapatite nanoparticles (n-HA).
• Characterization using High-Resolution Transmission Electron Microscopy (HRTEM), Fourier-Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), and UV-visible spectroscopy.

Main Results:

• Successful functionalization of n-HA with Naringin was confirmed.
• Characterization techniques verified the formation and properties of the NA-functionalized n-HA.

Conclusions:

• Naringin functionalized hydroxyapatite nanoparticles are synthesized and characterized.
• The developed NA-functionalized n-HA shows promise as a biomaterial for bone regeneration in medical and dental fields.