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Alcohol-associated bowel disease: new insights into pathogenesis

Luca Maccioni1,2, Yaojie Fu1, Yves Horsmans3

  • 1Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA.

Egastroenterology
|September 4, 2023
PubMed
Summary

Excessive alcohol intake causes alcohol-associated bowel disease (ABD) through gut barrier dysfunction. Ethanol metabolism to acetaldehyde and acetate may drive these changes and contribute to digestive tract cancers.

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