Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 17, 2025

A Microfluidic Platform for High-throughput Single-cell Isolation and Culture
09:51

A Microfluidic Platform for High-throughput Single-cell Isolation and Culture

Published on: June 16, 2016

11.5K

Full-electric microfluidic platform to capture, analyze and selectively release single cells.

Ruben Van den Eeckhoudt1, An-Sofie Christiaens2, Frederik Ceyssens1,3

  • 1Micro- and Nanosystems (MNS), Department of Electrical Engineering (ESAT), KU Leuven, Leuven, Belgium. ruben.vandeneeckhoudt@kuleuven.be.

Lab on a Chip
|September 5, 2023
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intron location and sequence modulate gene expression in Yarrowia lipolytica.

Nucleic acids research·2026
Same author

Fluorescent carbon dot-based biosensor for the rapid and sensitive detection of Escherichia coli DNA.

Scientific reports·2026
Same author

A curved-beam piezoelectric MEMS resonator featuring multiple temperature plateaus with enhanced stability.

Microsystems & nanoengineering·2026
Same author

A capacitive-piezoelectric hybrid MEMS microphone with signal fusion for enhancing signal-to-noise ratio.

Microsystems & nanoengineering·2026
Same author

A cochlea bio-inspired tunable piezoelectric cantilever array MEMS microphone: comprehensive study.

Microsystems & nanoengineering·2026
Same author

Hidden threats: exploring biofilm communities in broiler houses and pig nursery units drinking water lines.

BMC microbiology·2026
This summary is machine-generated.

We developed a novel microfluidic device for full-electric single-cell analysis, enabling precise cell capture, analysis, and release. This technology offers a miniaturized, automated solution for high-throughput cell studies.

Area of Science:

  • Biotechnology
  • Microfluidics
  • Electrical Engineering

Background:

  • Current single-cell technologies are limited by expensive, large equipment.
  • There is a need for accessible, miniaturized single-cell analysis tools.

Purpose of the Study:

  • To present a novel microfluidic device for integrated, full-electric single-cell manipulation.
  • To demonstrate cell capturing, analysis, and selective release with single-cell resolution.

Main Methods:

  • Development of a microfluidic platform with coplanar electrodes for cell trapping.
  • Implementation of a Two-Voltage method using positive dielectrophoresis (pDEP) for controlled cell capture.
  • Utilizing broadband electrochemical impedance spectroscopy for cell analysis and parameter extraction.

More Related Videos

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

15.0K
Cell Capture Using a Microfluidic Device
29:02

Cell Capture Using a Microfluidic Device

Published on: October 1, 2007

5.5K

Related Experiment Videos

Last Updated: Jul 17, 2025

A Microfluidic Platform for High-throughput Single-cell Isolation and Culture
09:51

A Microfluidic Platform for High-throughput Single-cell Isolation and Culture

Published on: June 16, 2016

11.5K
A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

15.0K
Cell Capture Using a Microfluidic Device
29:02

Cell Capture Using a Microfluidic Device

Published on: October 1, 2007

5.5K

Main Results:

  • Successful demonstration of single-cell trapping, analysis, and selective release on Saccharomyces cerevisiae.
  • Established a correlation between phase change and cell size for biological size measurements.
  • Validated the Two-Voltage method for precise control over cell trapping.

Conclusions:

  • The developed microfluidic device offers a full-electric, miniaturized, and automatable platform for single-cell analysis.
  • This technology opens new possibilities for small-scale, high-throughput single-cell analysis and sorting.
  • The system shows potential for integration into lab-on-CMOS devices.