Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 17, 2025

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM
19:16

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM

Published on: August 5, 2009

16.0K

Measuring picometre-level displacements using speckle patterns produced by an integrating sphere.

Morgan Facchin1, Graham D Bruce2, Kishan Dholakia3,4,5

  • 1SUPA, School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, KY16 9SS, UK. mf225@st-andrews.ac.uk.

Scientific Reports
|September 5, 2023
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Speckle-based measurement of the fractional azimuthal index of orbital angular momentum beams for refractive index sensing.

Nature communications·2026
Same author

Superconducting nanowire single-photon detectors for enhanced biomedical imaging.

Journal of biomedical optics·2026
Same author

CO<sub>2</sub> Isotopologue Quantification Using Direct Frequency Comb Spectroscopy and Machine Learning.

ACS omega·2025
Same author

The role of light sheet microscopy for non-invasive imaging of live embryos.

Human reproduction (Oxford, England)·2025
Same author

Shining a Light on the Future of Biophotonics.

Journal of biophotonics·2025
Same author

Sidelobe suppressed Bessel beams for one-photon light-sheet microscopy.

Biomedical optics express·2024

This study introduces a novel method for sub-nanometer displacement sensing using light speckle patterns within an integrating sphere. This technique achieves high precision, enabling sensitive measurements of nanoscale movements.

Area of Science:

  • Physics
  • Optical Engineering
  • Metrology

Background:

  • Advancements in optical microscopy, semiconductor technology, and fundamental science necessitate precision sensing at the nanoscale.
  • There is a growing need for displacement and position sensors capable of sub-nanometer accuracy.

Purpose of the Study:

  • To demonstrate a novel method for highly sensitive sub-nanometer displacement sensing.
  • To utilize light speckle patterns within an integrating sphere as a probe for nanoscale motion.

Main Methods:

  • An integrating sphere was divided into two independent hemispheres, with one hemisphere designed for controlled movement.
  • The relative motion between hemispheres was analyzed by observing changes in the generated light speckle pattern.
  • Analytical methods were employed to infer displacement amplitude from speckle pattern variations.

More Related Videos

Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

9.4K
Micro/Nano-scale Strain Distribution Measurement from Sampling Moir&#233; Fringes
06:56

Micro/Nano-scale Strain Distribution Measurement from Sampling Moiré Fringes

Published on: May 23, 2017

12.3K

Related Experiment Videos

Last Updated: Jul 17, 2025

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM
19:16

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM

Published on: August 5, 2009

16.0K
Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

9.4K
Micro/Nano-scale Strain Distribution Measurement from Sampling Moir&#233; Fringes
06:56

Micro/Nano-scale Strain Distribution Measurement from Sampling Moiré Fringes

Published on: May 23, 2017

12.3K

Main Results:

  • The developed method achieved a noise floor of 5 picometers per root Hertz (pm/rtHz) above 30 Hz.
  • The technique successfully measured oscillations with an amplitude of 17 picometers (pm).
  • A signal-to-noise ratio of 3 was achieved for the measured oscillations.

Conclusions:

  • Speckle patterns from light reflections inside an integrating sphere offer a highly sensitive method for displacement sensing.
  • The facile implementation allows for precise measurement of sub-nanometer displacements, crucial for nanoscale applications.
  • This technique provides a viable solution for demanding precision sensing requirements in advanced scientific fields.