The relationship between toxocara ELISA absorbance values and toxocara ELISA titres: a comparative study

Enzyme-linked immunosorbent assays (ELISAs) may be made by a variety of techniques at one or several serum dilutions which is very confusing for clinicians. This study compares the ELISA results from two centres on sera from 12 patients investigated for ocular toxocariasis by two common ELISA methods--the absorbance and titration techniques. With one exception, ELISA results by the two methods correlated well. For reasons outlined, the absorbance ELISA method is likely to remain the preferred method in New Zealand and Australia. Attention is drawn to the implications of the serum response to Toxocara canis larvae, and the need to evaluate ELISA results against clinical findings is emphasized.