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Updated: Jul 17, 2025
Establishing In Situ Closed Circuit Perfusion of Lower Abdominal Organs and Hind Limbs in Mice
Published on: August 13, 2020
[Possibilities of tissue perfusion assessment in abdominal surgery: integration into the intraoperative system of
V A Kashchenko1,2, A A Kamshilin1,3, V V Zaitsev1,3
1North-Western District Scientific and Clinical Center named after L.G. Sokolov of the Federal Medical and Biological Agency, St. Petersburg, Russia.
Objective:
To evaluate the possibility of integrating tissue perfusion assessment techniques (ICG perfusion and imaging photoplethysmography - iPPG) into the system of intraoperative control points of laparoscopic interventions with a reconstructive component.
Materials And Methods:
Quantitative assessment of ICG fluorescence and iPPG were used during 8 laparoscopically assisted interventions: gastrectomy for gastric cancer (total - 2 and distal - 1) and colorectal resections (left-sided colorectal resections - 4 and right hemicolectomy - 1).
Results:
Four stages are presented for the assessment of tissue perfusion: initial assessment, before intestine transection, before anastomosis formation, and evaluation of anastomosis. From the point of view of the significance of clinical decision-making, the «before intestine transection» stage is of great importance, due to the ease of transferring the resection level to the optimal tissue perfusion zone.
Conclusion:
Integration of tissue perfusion assessment techniques into the system of intraoperative checkpoints is possible and promising.
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