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Zinc Ions Modulate YY1 Activity: Relevance in Carcinogenesis

Małgorzata Figiel1, Adam Kazimierz Górka1, Andrzej Górecki1

  • 1Faculty of Biochemistry, Biophysics and Biotechnology, Department of Physical Biochemistry, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.

Cancers
|September 9, 2023
PubMed
Summary

Zinc ions enhance the activity of the YY1 transcription factor, impacting cancer progression. This suggests zinc levels, not just protein levels, are key to regulating gene expression in tumors.

Keywords:
Yin Yang 1dimerizationintrinsically disordered proteinprotein–protein interactionzinc binding

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