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Numerical Investigation on High-Performance Cu-Based Surface Plasmon Resonance Sensor for Biosensing Application.

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A novel TiO2-Cu-BaTiO3 hybrid structure offers high-sensitivity biosensing using surface plasmon resonance (SPR). This design protects copper (Cu) from oxidation and enhances sensor performance for accurate, long-term detection.

Keywords:
barium titanatebiosensorcoppersensitivitysurface plasmon resonancetitanium oxide

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Surface Plasmon Resonance (SPR) sensors are crucial for biosensing.
  • Copper (Cu) offers high resolution for SPR sensors but is prone to oxidation.
  • Barium titanate (BaTiO3) and titanium dioxide (TiO2) can enhance sensor performance and stability.

Purpose of the Study:

  • To propose and numerically analyze a novel TiO2-Cu-BaTiO3 hybrid structure for enhanced biosensing.
  • To investigate the protective role of BaTiO3 and the enhancing effect of TiO2 in a modified Kretschmann configuration.
  • To achieve high sensitivity and resolution in SPR biosensing using a cost-effective and stable plasmonic material.

Main Methods:

  • Numerical simulation of a modified Kretschmann configuration.
  • Utilizing a hybrid structure comprising TiO2, Cu, and BaTiO3 layers.
  • Angular interrogation method for analyzing SPR curves.
  • Optimization of layer thicknesses for maximum performance.

Main Results:

  • The TiO2-Cu-BaTiO3 structure demonstrated high sensitivity (552°/RIU) and a high Figure of Merit (FOM) (136.97 RIU⁻¹).
  • BaTiO3 effectively protected the Cu film from oxidation, ensuring sensor stability.
  • TiO2 acted as an effective adhesive and enhancing layer, improving the interaction between the prism and Cu film.

Conclusions:

  • The proposed hybrid structure offers a promising solution for high-performance SPR biosensing.
  • This design enables accurate and sensitive long-term detection, overcoming the limitations of traditional plasmonic metals.
  • The integration of TiO2 and BaTiO3 with Cu presents a viable pathway for advanced biosensor development.