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Published on: May 17, 2024
Impact of Sire on Embryo Development and Pregnancy
M Sofia Ortega1, Kelsey N Lockhart2, Thomas E Spencer2
1Department of Animal and Dairy Sciences, University of Wisconsin-Madison, 1675 Observatory Drive.
Abstract:
The use of in vitro embryo production (IVP) has increased globally, particularly in the United States. Although maternal factors influencing embryo development have been extensively studied, the influence of the sire is not well understood. Sperm plays a crucial role in embryo development providing DNA, triggering oocyte maturation, and aiding in mitosis. Current sire fertility measurements do not consistently align with embryo production outcomes. Low-fertility sires may perform well in IVP systems but produce fewer pregnancies. Testing sires in vitro could identify characteristics affecting embryo development and pregnancy loss risk in IVP and embryo transfer programs.
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