Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Virtual Reality Education for Hospitalized Pediatric Patients Improves Intrinsic Motivation: A Prospective, Randomized Crossover Study.

Clinical pediatrics·2026
Same author

Andragogic Model Curriculum for One-Year ACGME-Accredited Fellowship Programs: Single-Center Educational Improvement Project.

JMIR medical education·2026
Same author

Remote Augmented Reality Versus Traditional Simulation for Team Leader Assessment in a Cardiac Arrest Scenario: Noninferiority Randomized Controlled Trial.

JMIR medical education·2026
Same author

Sound and Third-Person Perspective in Virtual Reality Improves Awe: A Prospective Study of Hospitalized Children and Caregivers.

Games for health journal·2026
Same author

Family Engagement With Pediatric Anesthetic Records: A Qualitative Study of Provider-Guardian Communication and Record Design.

Paediatric anaesthesia·2026
Same author

Non-technical skill performance during remote, international, augmented-reality neonatal resuscitation protocol simulations: a feasibility study.

BMC medical education·2026
Same journal

NRFit connectors: Implementation after the engineering solution.

Journal of clinical anesthesia·2026
Same journal

Retraction notice to 'The effect of play distraction on anxiety prior to pre-medication administration: A randomized trial' [Journal of Clinical Anesthesia 36 (2017) 27-31].

Journal of clinical anesthesia·2026
Same journal

Sodium bicarbonate alkalinization of local anesthetics for peripheral nerve blocks: A systematic review.

Journal of clinical anesthesia·2026
Same journal

Dynamic changes in oxygen-hemoglobin affinity during liver transplantation.

Journal of clinical anesthesia·2026
Same journal

AI-assisted interpretation of arterial blood gases using a hybrid Stewart and standard base excess model.

Journal of clinical anesthesia·2026
Same journal

Corrigendum to "Effect of midodrine on orthostatic intolerance after hip and knee arthroplasty: A randomized controlled trial (the MOBiLE study)" [Journal of Clinical Anesthesia, Volume 113 (2026), 112261].

Journal of clinical anesthesia·2026
See all related articles

Related Experiment Video

Updated: Jul 16, 2025

Virtual Reality Experiments with Physiological Measures
07:09

Virtual Reality Experiments with Physiological Measures

Published on: August 29, 2018

12.8K

Virtual reality facilitated exercise improves pain perception: A crossover study.

Samuel T Rodriguez1, Nathan Makarewicz2, Ellen Y Wang1

  • 1Stanford Chariot Program, Lucile Packard Children's Hospital Stanford, Palo Alto, CA, USA; Department of Anesthesiology, Perioperative, and Pain Medicine, Division of Pediatric Anesthesiology, Stanford School of Medicine, Stanford, CA, USA.

Journal of Clinical Anesthesia
|September 14, 2023
PubMed
Summary
This summary is machine-generated.

Virtual reality (VR)-facilitated exercise significantly reduced pain sensitivity in a clinical trial. This innovative approach may improve pain perception for individuals undergoing physical therapy or managing chronic pain.

Keywords:
AnesthesiaExercisePainPain perceptionPhysical therapyVirtual reality

More Related Videos

The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living
08:36

The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living

Published on: July 28, 2022

3.8K
A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients
05:54

A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients

Published on: May 16, 2025

258

Related Experiment Videos

Last Updated: Jul 16, 2025

Virtual Reality Experiments with Physiological Measures
07:09

Virtual Reality Experiments with Physiological Measures

Published on: August 29, 2018

12.8K
The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living
08:36

The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living

Published on: July 28, 2022

3.8K
A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients
05:54

A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients

Published on: May 16, 2025

258

Area of Science:

  • Pain management research
  • Virtual reality applications in health
  • Exercise physiology

Background:

  • Virtual reality (VR) and exercise independently offer analgesic and anxiolytic benefits.
  • Understanding combined effects of VR and exercise on pain modulation is crucial.

Purpose of the Study:

  • To evaluate the efficacy of VR-facilitated exercise in modulating pain perception.
  • To assess the impact of VR-facilitated exercise on pain sensitivity, tolerance, and sympathetic activation.

Main Methods:

  • A within-subject, cross-over clinical trial was conducted with healthy participants.
  • Participants underwent a standardized cold pressor test under two conditions: no VR/exercise and VR-facilitated exercise.
  • Pain sensitivity, pain tolerance, and skin conductance response density (SCRD) were measured.

Main Results:

  • VR-facilitated exercise significantly reduced pain sensitivity (p < 0.0001).
  • No significant difference in pain tolerance was observed between conditions.
  • Sympathetic activation, measured by SCRD, was higher throughout the VR-facilitated exercise condition.

Conclusions:

  • VR-facilitated exercise demonstrates potential for improving pain perception.
  • This intervention may be beneficial for patients with chronic pain or those requiring physical therapy.
  • Further research can explore VR-facilitated exercise in diverse clinical populations.